Sarcosine

Sarcosine， a natural amino acid found in muscles and other body tissues， is an endogenous glycine transporter type 1 inhibitor that increases the glycine concentration， resulting in an indirect potentiation of the N-methyl-D-aspartate (NMDA) subtype of glutamate receptors. Sarcosine， similar to other NMDA receptor-activating agents， is an effective adjuvant in the treatment of schizophrenia.Sarcosine， a glycine transporter type 1 inhibitor and an N-methyl-D-aspartate (NMDA) receptor co-agonist at the glycine binding site， potentiates NMDA Receptor function. [1-2].