IM2650-5mg

mLN-2480 is a potent and selective Pan-Raf kinase inhibitor. Raf kinases (A-Raf, B-Raf and C-Raf) are key regulators of cell proliferation and survival in the mitogen-activated protein kinase (MAPK) pathway. The MAPK pathway is frequently dysregulated in human cancers, usually through activating Ras or Raf mutations.