IM2100-5mg

ML347 (LDN193719) is a highly selective ALK1/ALK2 inhibitor. ML347 has IC50 values of 46 and 32 nM against ALK1 and ALK2， respectively， >300-fold selective over ALK3. ML347 block the phosphorylation of Smad1/5 by TGF-β1[1-2].