HPV type 2

Inactivated Human Parainfluenza Virus 2 Antigen Cat.No:DAG206 Lot. No. (See product label) PRODUCT INFOMATION Storage Store at70oC. Storage in frostfree freezers is not recommended. This product shouldbe stored undiluted. Avoid repeated freezing and thawing as this may denaturethe protein. Format Inactivated Pathogen Applications ELISA Key words Human parainfluenza viruses; HPIVs;HPIV2; HPIV; Human Parainfluenza virus 2; Paramyxoviridae Target Species Viral Activity Thisproduct has been rendered inactive by standard procedures. However thismaterial should still be handled as infectious and should be disposed ofappropriately. Buffer Solution TissueCulture Media Preservative None present Stabilisers Preparation Optimallyinfected monolayers are harvested, disrupted by sonication and subjected tolow speed centrifugation. The clarified cell lysate is pooled withsupernatant from the infected culture and concentrated using crossflowultrafiltration with a 30,000 molecular cutoff. The antigen preparation isinactivated using gamma radiation. Shelf Life 18 months from dateof dispatch. Background Introduction HPIV is genetically and antigenicallydivided into types 1 to 4. HPIV 1 to HPIV 3 are major causes of lowerrespiratory infections in infants, young children, the immunocompromised, thechronically ill, and the elderly. Each subtype can cause somewhat uniqueclinical diseases in different hosts. HPIV are enveloped and of medium size(150 to 250 nm), and their RNA genome is in the negative sense. These virusesbelong to the Paramyxoviridae family, one of the largest and most rapidlygrowing groups of viruses causing significant human and veterinary disease.HPIV are closely related to recently discovered megamyxoviruses (Hendra andNipah viruses) and metapneumovirus. Creative Diagnostics. All rights reserved 4516 Ramsey Road Shirley, NY 11967, USA Tel: 6316244882 ·Fax:6316147828 Email: info@creativediagnostics.com www.creativediagnostics.com