Mumps Virus
SPECIFICATION SHEET
Rev 111114AGZSS007
Inactivated Mumps Virus Antigen
Antigen (Mumps Virus)
Cat. No: DAG202
Lot.No: (See product label)
PRODUCT INFORMATION BACKGROUND
Product Overview: Inactivated Mumps Virus anti Introduction: Mumps virus is the causative agent of
gen by gamma radiation. mumps, a wellknown common childhood disease
Antigen Description: The mumps virus is a mem characterised by swelling of the parotid glands and
ber of the Paramyxoviridae family and is the causa other epithelial tissues, causing high morbidity and in
tive agent of mumps. Mumps is most typically char some cases more serious complications such as deaf
acterised by painful swelling of the salivary glands ness. Mumps virus belongs to the genus Rubulavirus
and fever. Infected individuals are contagious from in the family Paramyxoviridae and is seen to have a
approximately 6 days before until about 9 days after roughly spherical, enveloped morphology of about
the onset of symptoms. The disease is selflimiting 200 nm in diameter. It contains a linear, single
and treatment involves controlling specific symptoms. stranded molecule of negativesense RNA 15,384
An effective vaccine exists and may be given sepa nucleotides long.
rately or as part of the MMR vaccine. PIP014 con Keywords: Mumps Virus; NP; Mumps Virus antigen;
tains a high concentration of virus and viral compo Paramyxoviridae; Rubulavirus
nents. The preparation also contains some cellular
material suspended in 1969B.
Product Form: Inactivated Mumps virus liquid PACKAGING
Target Species: Viral
Source: Mumps virus, Enders strain, cultured in Preservative Stabilisers: None present
BSC1 cells. Approx. Protein Concentrations: Total protein con
Format: Inactivated Pathogen centration 2.26 mg/ml
Preparation: Optimally infected cells are harvested, Shelf Life: 18 months from date of despatch.
disrupted by sonication in culture medium and sub Storage: Store at 70°C. Storage in frostfree freezers
jected to low speed centrifugation. The supernatant is not recommended. This product should be stored
from the infected culture is concentrated by cross undiluted. Avoid repeated freezing and thawing as this
flow ultrafiltration. The antigen preparation is inacti may denature the protein.
vated using gamma radiation, which primarily dam
ages viral genetic material.
Applications: ELISA
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