Recombinant SETD6 protein

SETD3 (SET Domain Containing 3, Actin Histidine Methyltransferase), is a protein-histidine N-methyltransferase that specifically mediates methylation of actin at 'His-73'. Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery. According to researches, SETD3 does not have proteinlysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin.