CENP-B (Centromere protein B) is a protein associated with centromeric DNA and crucial to the formation of the special chromatin...
EX-527 is a selective Sirtuin (SIRT1) inhibitor (IC50 = 98 nM). It does not inhibit other HDACs or SIRT family members. EX-527...
PDX1 (pancreatic and duodenal homeobox 1, GSF, IPF1, IUF1, IDX-1, MODY4, PDX-1, STF-1) activates insulin, somatostatin, glucokinase,...
Vorinostat (SAHA) is a potent and selective histone deacetylase (HDAC) inhibitor that induces apoptosis in a variety of tumor cell...
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