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IkBa phospho Ser32,36 mouse antibody (mAb) (Clone 39A1431) (100 µg)

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40904

Description

IκBα phospho Ser32,36 – NFκB (NFκB p50 and NFκB p65) signaling is controlled to a large extent by the sequestration of the NFκB complex in the cytoplasm by its association with one of the IκB family of proteins. IκBα is phosphorylated at Ser32 and Ser36 by the IκB Kinase (IKK) complex, resulting in the degradation of IκB and the nuclear translocation of NFκB.

Specifications


Application Notes

Validated Applications:
WB: 1 - 2 µg/ml dilution

Published Applications: see references

For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.1% Tween 20 to all Blotto solutions may also reduce background. Individual optimization may be required.
Immunogen
This IκBα phospho Ser32,36 antibody was raised against a synthetic peptide containing phosphorylated serines at amino acid residues 32 and 36 of human IκBα.
Buffer
PBS containing 0.02% sodium azide. Sodium azide is highly toxic.
Storage
Antibodies in solution can be stored at -80°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Guaranteefor IkBa phospho Ser32,36 antibody (mAb) (Clone 39A1431)Guarantee
This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

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